Ozempic Face: What You Need to Know

“Ozempic Face,” a non-medical side effect of rapid weight loss with GLP-1 medications, is becoming more widespread as the drug gains popularity. However, there are preventions and treatments that can minimize these effects.

In recent years, Ozempic has gained widespread attention, not only for its ability to control type 2 diabetes but for its impressive effects on weight loss. As more people turn to the drug containing the active ingredient semaglutide, it has sparked a wave of interest about its potential to help with weight loss. However, along with its growing popularity, there has been increasing debate about possible side effects, one of the most talked about being the phenomenon known as “Ozempic face.”

Ozempic is a medication that is primarily used to control blood sugar levels in adults with type 2 diabetes while also helping to lose weight. It works by mimicking a natural protein in the body called glucagon-like peptide 1 (GLP-1). By activating GLP-1 receptors, Ozempic increases insulin production, which helps control blood sugar and curb appetite, making it an effective tool for both diabetes management and weight loss. .

What is the Ozempic face?

ozempica face is a non-medical term used to describe facial changes that can occur as a result of rapid weight loss. “Dermatologist Hannah Kopelman states: “When we talk about ‘Ozempic face’, it is essentially the result of significant weight loss, particularly rapid weight loss, which causes a reduction of the underlying fat in the face. This fat helps give volume to our face and a youthful and full appearance.” When we lose weight, especially at a rapid rate, we lose fat not only from our body but also from our face. As we lose that fat, especially quickly, the skin may show signs of sagging, more pronounced wrinkles, and take on a gaunt or hollow appearance.

Symptoms of ozempica face

  • Facial fat loss: The most notable difference from Ozempic Face is the loss of fat under the skin.
  • Flabby, sagging skin: The skin may become loose as it struggles to adapt to the fat reduction.
  • Pronounced features: As facial fat decreases, bones and features such as the cheekbones and jaw may appear sharper.
  • Wrinkled and aged skin: Without the fat that gives volume to the skin, it may look more wrinkled or aged, especially around the forehead, eyes and mouth.
  • Haggard look: The face may take on a more hollow or sunken appearance.

It is important to note that this phenomenon is not unique to Ozempic. Kopelman says that “it can occur with any form of significant weight loss, but has been highlighted with the use of Ozempic because of how quickly patients lose weight on these medications.” Other GLP-1 medications such as Wegovy, Zepbound and Mounjaro It can also cause the same symptoms.

“What really plays a big role here is the speed at which you lose the weight,” explains Kopelman. “With rapid weight loss, the skin does not have as much time to adapt and retract, causing more noticeable sagging and emaciated appearance. “Slower, more gradual weight loss tends to be gentler on the skin, allowing it to adapt and potentially minimize these effects, although some skin laxity and volume loss are inevitable with any substantial weight loss.”

How to avoid ozempic face

Since Ozempic Face is not a formal condition, there is no official medical treatment. However, there are steps you can take to minimize its impact:

Avoid rapid weight loss. A slower, steady approach to losing weight can give your skin time to adapt, reducing sagging. If you notice signs of Ozempic facial development, talk to your doctor about reducing your dosage to prevent more symptoms from occurring while you continue to lose weight.

Eat a healthy and balanced diet. Focus on whole foods, including lean proteins, whole grains, and plenty of fruits and vegetables. Nutrients such as omega-3s, found for example in fish and flax seeds, help keep the skin hydrated. Vitamin C, on the other hand, can also help fight wrinkles by increasing collagen production.


Stay hydrated. Hydration is key to maintaining skin elasticity and avoiding a dull and wrinkled appearance. Drinking plenty of water and consuming fruits and vegetables with high water content, such as cucumbers and watermelons, can contribute to healthy skin.


Use skin care products:
For those who want to get ahead of prevention, Kopelman recommends focusing on ingredients that help with skin hydration and collagen support. Look for moisturizers and serums with:

  • Hyaluronic acid (helps plump skin by attracting water and peptides, which can support collagen production) (Try HUM’s Hyaluronic Glow Gummies to boost hydrated collagen.)
  • Retinoids (can improve skin elasticity and reduce the appearance of wrinkles. Kopelman notes that retinoids should be used with caution, especially if skin is already sensitive due to rapid weight loss)
  • Antioxidants (e.g., vitamin C) (helps protect skin from environmental damage and may increase collagen production)
  • Niacinamide (helps overall skin health and barrier repair, keeping skin looking more youthful)
  • Sunscreen (using daily can help minimize premature aging, wrinkles, and sagging skin that can come from spending too much time in the sun.)
  • HUMs Collagen Love contains collagen peptides that help with skin elasticity and firming. It also has vitamin C that fights skin damage and hyaluronic acid for plump, glowing skin.

In addition to professional treatments, it is essential to maintain a consistent routine at home to care for your skin. The same skin care products you use to prevent Ozempic facial signs can also help address and treat any appearance that develops. Additionally, the same concept applies to continuing a nutritious diet. Eating a variety of whole foods provides your body with essential vitamins and minerals to promote healthier, younger-looking skin, and works as a preventative measure and as a way to treat signs of aging.

The conclusion about Ozempic’s face

Although Ozempic Face is not a medical condition, it is a cosmetic problem that can affect your confidence as a result of rapid weight loss. To reduce the likelihood of experiencing these changes, aim for gradual weight loss, prioritize a nutritious diet, stay well hydrated, and incorporate effective skin care products. If you are already noticing signs of facial aging, treatments such as dermal fillers or PRP can help rejuvenate your appearance and restore volume for a more youthful appearance.

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